Title

How to detect carbapenemase producers? A literature review of phenotypic and molecular methods

Source of Publication

Journal of Microbiological Methods

Abstract

© 2014 Elsevier B.V. This review describes the current state-of-art of carbapenemase detection methods. Identification of carbapenemases is first based on conventional phenotypic tests including antimicrobial susceptibility testing, modified-Hodge test and carbapenemase-inhibitor culture tests. Second, molecular characterization of carbapenemase genes by PCR sequencing is essential. Third, innovative biochemical and spectrometric detection may be applied.

Document Type

Article

First Page

106

Last Page

118

Publication Date

12-1-2014

DOI

10.1016/j.mimet.2014.09.009

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