Title

Rapid detection of sulfamethoxazole in plasma and food samples with in-syringe membrane SPE coupled with solid-phase fluorescence spectrometry

ORCID Identifiers

0000-0001-7558-3608

Document Type

Article

Source of Publication

Food Chemistry

Publication Date

8-1-2020

Abstract

© 2020 Elsevier Ltd In this work, in-syringe membrane solid-phase extraction (MSPE) device was fabricated for the on-site sampling of sulfamethoxazole (SMX) in food samples followed by solid-phase fluorescence spectra analysis. The samples and fluorescamine (FA) were added to a syringe for derivation. Then, the derivative of SMX was extracted by a membrane in the syringe SPE device. Subsequently, the derivative on the membrane was measured immediately without additional elution procedure. The method was successfully applied in plasma, milk, and egg samples for the trace SMX detection, with the recovery of 98%–102%, RSDs from 1% to 6%. Compared with liquid chromatography, direct detection of the concentrated analyte significantly improved the sensitivity. Moreover, fluorescamine made it unnecessary to separate SMX from the interference. Consequently, it was a time-saving, low-cost, and easy-operation method, which demonstrated the potential of in-syringe SPE as a promising candidate for on-site analysis.

ISSN

0308-8146

Publisher

Elsevier Ltd

Volume

320

First Page

126612

Disciplines

Life Sciences

Keywords

Fluorescamine, Food samples, In-syringe solid-phase extraction, Solid-phase fluorescence, Sulfamethoxazole

Scopus ID

85081677677

Indexed in Scopus

yes

Open Access

no

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