Document Type

Article

Source of Publication

Journal of cancer prevention

Publication Date

3-30-2016

Abstract

Nitric oxide (NO) in general plays a beneficial physiological role as a vasorelaxant and the role of NO is decided by its concentration present in physiological environments. NO either facilitates cancer-promoting characters or act as an anti-cancer agent. The dilemma in this regard still remains unanswered. This review summarizes the recent information on NO and its role in carcinogenesis and tumor progression, as well as dietary chemopreventive agents which have NO-modulating properties with safe cytotoxic profile. Understanding the molecular mechanisms and cross-talk modulating NO effect by these chemopreventive agents can allow us to develop better therapeutic strategies for cancer treatment.

ISSN

2288-3649

Publisher

Korean Society of Cancer Prevention

Volume

21

Last Page

12

Disciplines

Medicine and Health Sciences

Keywords

Chemoprevention; Endothelial nitric oxide synthase; Inducible nitric oxide synthase; Neoplasms; Nitric oxide

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

Indexed in Scopus

no

Open Access

yes

Open Access Type

Gold: This publication is openly available in an open access journal/series

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