Source of Publication
World Journal of Hepatology
© 2015 Baishideng Publishing Group Inc. The purpose of this article review is to update what is known about the role of diet on non-alcoholic fatty liver disease (NAFLD). NAFLD is the most common cause of chronic liver disease in the developed world and is considered to be a spectrum, ranging from fatty infiltration of the liver alone (steatosis), which may lead to fatty infiltration with inflammation known as non alcoholic steatohepatitis While the majority of individuals with risk factors like obesity and insulin resistance have steatosis, only few people may develop steatohepatitis. Current treatment relies on weight loss and exercise, although various insulin-sensitizing medications appear promising. Weight loss alone by dietary changes has been shown to lead to histological improvement in fatty liver making nutrition therapy to become a cornerstone of treatment for NAFLD. Supplementation of vitamin E, C and omega 3 fatty acids are under consideration with some conflicting data. Moreover, research has been showed that saturated fat, trans-fatty acid, carbohydrate, and simple sugars (fructose and sucrose) may play significant role in the intrahepatic fat accumulation. However, true associations with specific nutrients yet to be clarified.
Baishideng Publishing Group Co
Medicine and Health Sciences
Diet, Fatty acids, Insulin resistance, Non-alcoholic fatty acids, Obesity
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Papandreou, Dimitrios and Andreou, Eleni, "Role of diet on non-alcoholic fatty liver disease: An updated narrative review" (2015). All Works. 3002.
Indexed in Scopus
Open Access Type
Gold: This publication is openly available in an open access journal/series