Source of Publication
Cancer is the second leading cause of death after cardiovascular diseases. Conventional anticancer therapies are associated with lack of selectivity and serious side effects. Cancer hallmarks are biological capabilities acquired by cancer cells during neoplastic transformation. Targeting multiple cancer hallmarks is a promising strategy to treat cancer. The diversity in chemical structure and the relatively low toxicity make plant-derived natural products a promising source for the development of new and more effective anticancer therapies that have the capacity to target multiple hallmarks in cancer. In this review, we discussed the anticancer activities of ten natural products extracted from plants. The majority of these products inhibit cancer by targeting multiple cancer hallmarks, and many of these chemicals have reached clinical applications. Studies discussed in this review provide a solid ground for researchers and physicians to design more effective combination anticancer therapies using plant-derived natural products.
Medicine and Health Sciences
Plant-derived natural products, Alternative cancer therapies, Anticancer, Apoptosis induction, Plants
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This work is licensed under a Creative Commons Attribution 4.0 International License.
Talib, Wamidh H.; Daoud, Safa; Mahmod, Asma Ismail; Hamed, Reem Ali; Awajan, Dima; Abuarab, Sara Feras; Odeh, Lena Hisham; Khater, Samar; and Al Kury, Lina T., "Plants as a Source of Anticancer Agents: from Bench to Bedside" (2022). All Works. 5320.
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Open Access Type
Gold: This publication is openly available in an open access journal/series