Maternal Early-Life Risk Factors and Later Gestational Diabetes Mellitus: A Cross-Sectional Analysis of the UAE Healthy Future Study (UAEHFS)
Source of Publication
International Journal of Environmental Research and Public Health
Limited studies have focused on maternal early-life risk factors and the later development of gestational diabetes mellitus (GDM). We aimed to estimate the GDM prevalence and examine the associations of maternal early-life risk factors, namely: maternal birthweight, parental smoking at birth, childhood urbanicity, ever-breastfed, parental education attainment, parental history of diabetes, childhood overall health, childhood body size, and childhood height, with later GDM. This was a retrospective cross-sectional study using the UAE Healthy Future Study (UAEHFS) baseline data (February 2016 to April 2022) on 702 ever-married women aged 18 to 67 years. We fitted a Poisson regression to estimate the risk ratio (RR) for later GDM and its 95% confidence interval (CI). The GDM prevalence was 5.1%. In the fully adjusted model, females with low birthweight were four times more likely (RR 4.04, 95% CI 1.36-12.0) and females with a parental history of diabetes were nearly three times more likely (RR 2.86, 95% CI 1.10-7.43) to report later GDM. In conclusion, maternal birthweight and parental history of diabetes were significantly associated with later GDM. Close glucose monitoring during pregnancy among females with either a low birth weight and/or parental history of diabetes might help to prevent GDM among this high-risk group.
Medicine and Health Sciences
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This work is licensed under a Creative Commons Attribution 4.0 International License.
Juber, Nirmin F.; Abdulle, Abdishakur; AlJunaibi, Abdulla; AlNaeemi, Abdulla; Ahmad, Amar; Leinberger-Jabari, Andrea; Dhaheri, Ayesha S. Al; AlZaabi, Eiman; Mezhal, Fatima; Al-Maskari, Fatma; AlAnouti, Fatme; Alsafar, Habiba; Alkaabi, Juma; Wareth, Laila Abdel; Aljaber, Mai; Kazim, Marina; Weitzman, Michael; Al-Houqani, Mohammad; Ali, Mohammed Hag; Oumeziane, Naima; El-Shahawy, Omar; Sherman, Scott; AlBlooshi, Sharifa; Shah, Syed M.; Loney, Tom; Almahmeed, Wael; Idaghdour, Youssef; and Ali, Raghib, "Maternal Early-Life Risk Factors and Later Gestational Diabetes Mellitus: A Cross-Sectional Analysis of the UAE Healthy Future Study (UAEHFS)" (2022). All Works. 5347.
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Gold: This publication is openly available in an open access journal/series