How to detect carbapenemase producers? A literature review of phenotypic and molecular methods

Document Type

Article

Source of Publication

Journal of Microbiological Methods

Publication Date

12-1-2014

Abstract

© 2014 Elsevier B.V. This review describes the current state-of-art of carbapenemase detection methods. Identification of carbapenemases is first based on conventional phenotypic tests including antimicrobial susceptibility testing, modified-Hodge test and carbapenemase-inhibitor culture tests. Second, molecular characterization of carbapenemase genes by PCR sequencing is essential. Third, innovative biochemical and spectrometric detection may be applied.

ISSN

0167-7012

Publisher

Elsevier

Volume

107

First Page

106

Last Page

118

Disciplines

Life Sciences

Keywords

Carbapenemases, Detection, Molecular methods, Phenotypic methods, Screening

Scopus ID

84908620706

Indexed in Scopus

yes

Open Access

no

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