An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
Document Type
Article
Source of Publication
Journal of Molecular Liquids
Publication Date
10-1-2017
Abstract
© 2017 Ionic liquid due to its green nature as well as having the ability to dissolve biopolymer, was used in the preparation of collagen and alginate hydrogels. The collagen and alginate hydrogels were prepared in different ratios of collagen and alginate, labeled CA5040, CA6030 and CA7020. The prepared hydrogels were characterized with Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Thermogravimetric analysis (TGA) analysis. The samples were evaluated for water uptake behavior and mechanical properties using electrodynamic fatigue testing system. The biocompatibility was assessed through hemolysis and MTT assay on rat mesenchymal stem cells (rMSC) which showed satisfactory results. The drug loading and subsequent antibacterial properties were also performed. The prepared collagen and alginate hydrogels are suggested to be used for skin dressing.
DOI Link
ISSN
Publisher
Elsevier B.V.
Volume
243
First Page
720
Last Page
725
Disciplines
Life Sciences
Keywords
Biocompatibility, Collagen, Hydrogels, Ionic liquid, Skin dressing
Scopus ID
Recommended Citation
Iqbal, Bushra; Muhammad, Nawshad; Jamal, Arshad; Ahmad, Pervaiz; Khan, Zia Ul Haq; Rahim, Abdur; Khan, Amir Sada; Gonfa, Girma; Iqbal, Jibran; and Rehman, Ihtesham Ur, "An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing" (2017). All Works. 416.
https://zuscholars.zu.ac.ae/works/416
Indexed in Scopus
yes
Open Access
no