Document Type


Source of Publication

Informatics in Medicine Unlocked

Publication Date



COVID-19 detection from medical imaging is a difficult challenge that has piqued the interest of experts worldwide. Chest X-rays and computed tomography (CT) scanning are the essential imaging modalities for diagnosing COVID-19. All researchers focus their efforts on developing viable methods and rapid treatment procedures for this pandemic. Fast and accurate automated detection approaches have been devised to alleviate the need for medical professionals. Deep Learning (DL) technologies have successfully recognized COVID-19 situations. This paper proposes a developed set of nine deep learning models for diagnosing COVID-19 based on transfer learning and implementation in a novel architecture (SEL-COVIDNET). In which we include a global average pooling layer, flattening, and two dense layers that are fully connected. The model’s effectiveness is evaluated using balanced and unbalanced COVID-19 radiography datasets. After that, our model’s performance is analyzed using six evaluation measures: accuracy, sensitivity, specificity, precision, F1-score, and Matthew’s correlation coefficient (MCC). Experiments demonstrated that the proposed SEL-COVIDNET with tuned DenseNet121, InceptionResNetV2, and MobileNetV3Large models outperformed the results of comparative SOTA for multi-class classification (COVID-19 vs. No-finding vs. Pneumonia) in terms of accuracy (98.52%), specificity (98.5%), sensitivity (98.5%), precision (98.7%), F1-score (98.7%), and MCC (97.5%). For the COVID-19 vs. No-finding classification, our method had an accuracy of 99.77%, a specificity of 99.85%, a sensitivity of 99.85%, a precision of 99.55%, an F1-score of 99.7%, and an MCC of 99.4%. The proposed model offers an accurate approach for detecting COVID-19 patients, which aids in the containment of the COVID-19 pandemic.




Elsevier BV

First Page


Last Page



Computer Sciences | Medicine and Health Sciences


COVID-19, Transfer learning, X-ray images, CT-scans, Pneumonia, Deep Learning, Classification

Scopus ID


Indexed in Scopus


Open Access


Open Access Type

Gold: This publication is openly available in an open access journal/series