Associations between Polycystic Ovary Syndrome (PCOS) and Antibiotic Use: Results from the UAEHFS

Author First name, Last name, Institution

Nirmin F. Juber, NYU Abu Dhabi
Abdishakur Abdulle, NYU Abu Dhabi
Amar Ahmad, NYU Abu Dhabi
Fatme AlAnouti, Zayed UniversityFollow
Tom Loney, Mohammed Bin Rashid University of Medicine and Health Sciences
Youssef Idaghdour, NYU Abu Dhabi
Yvonne Valles, NYU Abu Dhabi
Raghib Ali, NYU Abu Dhabi

Document Type

Article

Source of Publication

Antibiotics

Publication Date

5-1-2024

Abstract

Women with polycystic ovary syndrome (PCOS) have a higher susceptibility to infections compared to those without PCOS. Studies evaluating antibiotic use based on PCOS status are scarce. Therefore, we aimed to (i) assess the associations between self-reported PCOS and antibiotic use, and (ii) whether PCOS treatment and the age at PCOS diagnosis modified the associations above. This cross-sectional analysis used the United Arab Emirates Healthy Future Study (UAEHFS) conducted from February 2016 to March 2023 involving 2063 Emirati women aged 18–62 years. We performed ordinal logistic regressions under unadjusted and demographic-health-characteristic-adjusted models to obtain the odds ratios (ORs) and 95% confidence intervals (CIs) to analyze PCOS and antibiotic use. Subgroup analyses were performed by treatment status and age at diagnosis. We found that women with PCOS were 55% more likely to frequently take a course of antibiotics in the past year (aOR 1.55; 95% CI 1.26–1.90). Similar likelihoods were also found among those being treated for PCOS and those without treatment but with a PCOS diagnosis at ≤25 years. Our study suggests that PCOS was associated with an increased use of antibiotics among Emirati women. Understanding the frequent antibiotic use susceptibility among those with PCOS may improve antibiotic use surveillance and promote antibiotic stewardship in these at-risk individuals.

DOI Link

10.3390/antibiotics13050397

ISSN

2079-6382

Publisher

MDPI AG

Volume

13

Issue

5

Disciplines

Medicine and Health Sciences

Keywords

antibiotic use, epidemiology, global health, PCOS, polycystic ovary syndrome

Scopus ID

85194029147

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Juber, Nirmin F.; Abdulle, Abdishakur; Ahmad, Amar; AlAnouti, Fatme; Loney, Tom; Idaghdour, Youssef; Valles, Yvonne; and Ali, Raghib, "Associations between Polycystic Ovary Syndrome (PCOS) and Antibiotic Use: Results from the UAEHFS" (2024). All Works. 6594.
https://zuscholars.zu.ac.ae/works/6594

Indexed in Scopus

yes

Open Access

yes

Open Access Type

Gold: This publication is openly available in an open access journal/series